Celine Dion leads star-studded lineup for Stand Up to Cancer live show

Celine Dion is set to take the stage at this year's Stand Up to Cancer Canada telecast. The songstress will perform live during the show, which will air simultaneously on all Canadian outlets on Sept. 9.

TAP FOR GALLERY Celine will perform at this year's Stand Up to Cancer Canada telecast on Sept. 9.

It will be an emotional and personal performance for the mother of three as she is still grieving the loss of her loving husband René Angélil and brother Daniel, both of whom passed away from cancer in January.

Now in its fifth year, the inspiring broadcast will also see support from Hollywood heavyweights like Ben Affleck, Matthew McConaughey and Emma Stone. Bradley Cooper has signed on as executive producer.

"We all have a reason to stand up,” said Bradley in a statement. He added: "We honour the personal stories that motivate individuals to fight, and that highlight the urgent need to get new treatments to the patients who so desperately need them."

Along with Celine, Keith Urban and Little Big Town will deliver emotionally charged performances during the one-hour show.

Past Stand Up To Cancer participants include Reese Witherspoon, Gwyneth Paltrow and Jennifer Aniston.

Reese Witherspoon and Jennifer Aniston appeared on the 2014 broadcast.

Stand Up to Cancer has also launched a new social media campaign in support of the broadcast. People are encouraged to share their own experiences with the disease through photos and video posts using the hashtag #Reasons2StandUp.

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