The 53-year-old actor spoke excitedly about the upcoming race in New York at the world premiere of his film The Secret Life of Walter Mitty, in which he stars alongside Ben Stiller.
"We've got five Haitian runners, 10 runners total, running for the team representing Haiti and our organization J/P HRO coming to the New York City Marathon... So we're really looking forward to it," he told the Associated Press.
The two-time Oscar-winner flew out to Haiti one week after the devastating 2010 earthquake and quickly made the crippled country his second home. He went on to become a major figure in the effort to rebuild, and in 2012 he was honoured for his work with the Peace Summit Award.
"It's rewarding,” he said when asked about his relief work. “I just came back from Port-au-Prince, where I visited our Haitian marathon runners, and to see that great discipline that Haitians have and that great spirit and the excitement that they have visiting New York for the first time."
Canadian actress and model Pamela Anderson recently gave her support to Sean’s organization, announcing that she will run in the marathon and attempt to raise $500,000 for the cause.
Other celebrities participating include Christy Turlington, who will be fundraising for international woman's charity Every Mother Counts, and Giuliana Rancic’s husband Bill, who is hoofing it for breast cancer group Fab-U-Wish.
The 42-kilometre marathon takes place Nov. 3.