Oprah Winfrey and her best friend Gayle King have spoken out in support of Duchess Meghan and Prince Harry's decision to step down from their senior royal roles.

Oprah, who is currently working on a mental health series for Apple TV+ with the Duke of Sussex, told TMZ that she supports the couple "1,000 per cent."

"I support them because I believe, when you have thought about this as long as they have - and even in the Queen's statement, [she] says, 'This has been going on for months,'" she told the outlet.

"And when Harry said in that charity statement the other day he had to make the decision to move forward in peace with his new family, who doesn't feel what that takes to make that decision to give up everything you've known your whole life to say, 'I'm going to choose this new life or what I believe to be the truest vision for myself'?"

"He did what he needed to do for his family," she continued. "I don't think anybody has the right to say anything."

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“After many months of reflection and internal discussions, we have chosen to make a transition this year in starting to carve out a progressive new role within this institution. We intend to step back as ‘senior’ members of the Royal Family and work to become financially independent, while continuing to fully support Her Majesty The Queen. It is with your encouragement, particularly over the last few years, that we feel prepared to make this adjustment. We now plan to balance our time between the United Kingdom and North America, continuing to honour our duty to The Queen, the Commonwealth, and our patronages. This geographic balance will enable us to raise our son with an appreciation for the royal tradition into which he was born, while also providing our family with the space to focus on the next chapter, including the launch of our new charitable entity. We look forward to sharing the full details of this exciting next step in due course, as we continue to collaborate with Her Majesty The Queen, The Prince of Wales, The Duke of Cambridge and all relevant parties. Until then, please accept our deepest thanks for your continued support.” - The Duke and Duchess of Sussex For more information, please visit sussexroyal.com (link in bio) Image © PA

A post shared by The Duke and Duchess of Sussex (@sussexroyal) on Jan 8, 2020 at 10:33am PST

In a separate interview with Entertainment Tonight, Gayle said she agreed with Oprah, and also said media speculation that the Queen was "blindsided" by the Duke and Duchess of Sussex's decision isn't helpful.

"I think that they made a decision that they think is best for them, and I know that I'm pulling for them 100 per cent," she said.

Last year, Gayle said she supported Harry and Meghan's move to keep their birth plans for Archie private. Photo: © Dimitrios Kambouris/WireImage

If you're wondering about news on Harry and Oprah's series, it looks like Lady Gaga will be part of it in some way. Mother Monster joined Oprah in Fort Lauderdale, Fla. on a stop of her recent "2020 Vision" tour, which was filmed for Oprah's YouTube channel and her SuperSoul Sunday podcast.

Oprah told the audience Gaga, who has been outspoken about her mental health, fibromyalgia and the connection between the two, would be involved in the series, which Harry is co-producing. It's not known what the nine-time GRAMMY winner's involvement will look like just yet, but we can't wait to watch!