The simple and elegant print ad, shot by fashion photographer Sølve Sundsbø, features Karlie's distinctive silhouette, as she holds the iconic perfume bottle to her face.
Despite having already walked numerous catwalks for Chanel, this is the first time that the 22-year-old has fronted one of the brand's campaigns, as she joins celebrities including Blake Lively and Keira Knightley as a face for the brand.
Karlie's past campaigns for high fashion labels including Marc Jacobs, Dior, Juicy Couture and of course, Victoria's Secret.
The young model recently revealed that fashion was not her only career choice, when she enrolled for a course at prestigious Ivy League school Harvard, to study The Business of Media, Entertainment and Sports. "I will fit in!" she told The Daily Front. "That is the great thing; I'm 20 years old! I feel fortunate to have an incredible career and experiences behind me, but there is so much more that I want to do with this career and my life."
"Harvard at some point is in the plan," she added. "But all in good time."